Exploring the World of Microbes and Gut Microbiome

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Discover the hidden world of microbes, where they live, their surprising resilience, and how they impact our gut microbiome. Learn about the benefits of certain microbes and the consequences of disrupting gut homeostasis. Explore the crosstalk between gut microbiota and circadian rhythms, along with fun experiments to better understand these tiny organisms.

  • Microbes
  • Gut microbiome
  • Bacteria
  • Gut health
  • Microbiology

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Presentation Transcript


  1. What is a microbe?

  2. Where do microbes live? Proper environment: humidity, temperature and gas Good energy resource: carbon and nitrogen

  3. Exceptions Places You Would Never Expect To Find Bacteria The cleanest place on earth: Nasa Clean Rooms In our case, [the spacecraft] is the patient. technical deputy program manager said. An entirely new genus of bacteria was discovered in not one, but two NASA clean rooms. Named Tersicoccus phoenicis ( Tersi is Latin for clean), this bacterium has earned a reputation for outwitting the most intense industrial cleaners and sterilization techniques.

  4. Boiling water Some bacteria, such as Clostridium botulinum, can survive in boiling water. Clostridium botulinum, which is responsible for botulism (a serious paralytic condition caused by a nerve toxin that can enter the body either through food intake or an open wound), prefers environments with relatively little oxygen, which is why it can grow and live in the most unnerving places, such as in your camp kettle or along the inside of a sealed can. it is best to use bleach, sodium hydroxide, and extreme temperatures (around 120 degrees Celsius) when trying to eradicate this pesky beast.

  5. Whats up with your gut microbiome?

  6. Questions: Did the video change your definition of what a microbe is? Are all microbes harmful or bad? How can some microbes benefit us?

  7. An example of the consequence when the homeostasis in the gut is disturbed?

  8. Crosstalk between the gut microbiota and circadian rhythms in the regulation of metabolism Gut microbiota also shows circadian rhythms in abundance Germ-free mice have distinct circadian rhythms Germ-free mice are leaner Obese people have different gut microbiota Fecal transplantation transfers the obesity phenotype Shiftwork Jetlag Mouse models Intestinal epithelial cells

  9. Fun Experiments Germ-Glow Observing your microbiota

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