Genome Editing for Sickle Cell Anemia Cure
Australian scientists have made a groundbreaking discovery in curing sickle cell anemia by editing the genome. By switching on a previously dormant gene, they aim to address the root cause of this blood disorder, potentially revolutionizing treatments for various blood diseases. Using advanced techniques like TALENs, researchers are exploring the insertion of a beneficial mutation into red blood cells to alleviate symptoms. This innovative approach could pave the way for effective management of genetic blood disorders in the future.
Download Presentation
Please find below an Image/Link to download the presentation.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author.If you encounter any issues during the download, it is possible that the publisher has removed the file from their server.
You are allowed to download the files provided on this website for personal or commercial use, subject to the condition that they are used lawfully. All files are the property of their respective owners.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author.
E N D
Presentation Transcript
SICKLE CELL ANEMIA COULD BE CURED BY GENOME EDITING By: Sophie Hogan
THE MAIN IDEA Australian scientists have found out that by changing one letter in DNA in the blood cells could be the beginning of the cure for sickle cell anemia and other blood diseases.
THE PROCESS The cure could work by switching on a sleeping gene that is on before you are born, but after you are born it turns off and a different version of the gene is turned on. The reason sickle cell anemia exists is because of a mutation in the adult hemoglobin. The research is based on people who have the mutation in the adult hemoglobin gene, but also have a mutation in the fetal hemoglobin gene. The mutation keeps the fetal gene on for the entire live of the person with sickle cell anemia. This gene being on can reduce the sickle cell anemia symptoms.
THE CURE The helpful mutation that was found by the UNSW scientists is inserted into the red blood cells using proteins called TALENs. According to the scientists, the TALENs can, cut a gene at a specific point, as well as providing the desired piece of donor DNA for insertion. Once the scientists figure out if this idea works and is safe, they can use this as a base to build other cure ideas off of and this could be used to cure other blood diseases.
THE SOURCE www.eurekalert.org/pub_releases/2015-05/uons-nao.php
