Challenging Fungal Infections: Chromoblastomycosis, Sporotrichosis, and more
Fungal infections like chromoblastomycosis, sporotrichosis, and opportunistic mycoses pose challenges in treatment. Candidiasis and aspergillosis are common fungal infections affecting different systems. Understanding the various types, symptoms, and treatment modalities is crucial in managing these conditions effectively.
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Presentation Transcript
Chromoblastomycosis Despite a variety of treatment modalities, which include long courses of antifungals, surgical excision and destructive physical therapies, the disease remains one of the most difficult deep mycotic infections to eradicate. Phaeohyphomycosis is a heterogeneous group of mycotic infections caused by dematiaceous fungi whose morphologic characteristics in tissue include hyphae, yeast-like cells, or a combination of these. It can be associated with darkly-pigmented
Sporotrichosis Sporothrix schenckii commonly occurs in nature as a saprophyte on dead plant material. Although this dimorphic mold is worldwide in distribution, it primarily grows in warm temperate and tropical climates.
Opportunistic mycoses fail to induce disease in most immunocompetent persons but can do so in those with impaired host defenses.There are five genera of medically important fungi: Candida, Cryptococcus, Aspergillus, Muc or, and Rhizopus.
Candidiasis the most important species of Candida, causes thrush, vaginitis, esophagitis, and chronic mucocutaneous candidiasis. It also causes disseminated infections such as right-sided endocarditis (especially in intravenous drug users),bloodstream infections (candidemia). Infections related to indwelling intravenous and urinary catheters are also important. Candida glabrata is the second most common cause of disseminated candidal infections and is more drug resistant than C. albicans.
Aspergillosis is an infection, allergic reaction, or fungal growth caused by the Aspergillus fungus. The fungus usually grows on decaying vegetation and dead leaves. Exposure to the fungus doesn t necessarily guarantee that you ll get aspergillosis. Almost everyone encounters the fungus on a daily basis and never contracts the illness. It s more likely to infect people with a weak immune system or a lung disease.Types of Aspergillosis and Their Symptoms different types of aspergillosis affect the body in different ways. Certain conditions and medications increase your risk for developing each type. Different types of aspergillosis have different symptoms.